1-[(2-chlorophenyl)methyl]-2-Piperazinemethanol
1-[(2-chlorophenyl)methyl]-2-Piperazinemethanol
CAS: 1267910-86-0
Molecular Formula: C12H17ClN2O
1-[(2-chlorophenyl)methyl]-2-Piperazinemethanol - Names and Identifiers
1-[(2-chlorophenyl)methyl]-2-Piperazinemethanol - Physico-chemical Properties
| Molecular Formula | C12H17ClN2O |
| Molar Mass | 240.73 |
1-[(2-chlorophenyl)methyl]-2-Piperazinemethanol - Introduction
1-[(2-Chlorophenyl) methyl]-2-piperazinemethanol is an organic compound with the chemical formula C'www.tianyancha.com H'www.tianyancha.com Cl₂ N₂ O. The following are some of the properties, uses, preparation and safety information about the compound:
Nature:
-Appearance: The compound was a white crystalline solid.
-Solubility: Insoluble in water, but soluble in organic solvents such as ethanol and dimethylformamide.
-Melting point: about 69-72 ℃.
-Stability: relatively stable under normal storage conditions.
Use:
-Drug: 1-[(2-chlorophenyl) methyl]-2-piperazine methanol, as a drug intermediate, can be used to synthesize drugs, with antidepressant and anti-anxiety properties.
Method:
The synthesis of 1-[(2-chlorophenyl) methyl]-2-piperazinemethanol is usually carried out by the following steps:
1.2-Chloroanisole reacts with piperazine to form 1-[(2-chlorophenyl) methyl]-2-piperazine methyl ether.
2.1-[(2-chlorophenyl) methyl]-2-piperazine methyl ether is reduced to 1-[(2-chlorophenyl) methyl]-2-piperazine methanol.
Safety Information:
- 1-[(2-Chlorophenyl) methyl]-2-piperazinemethanol should be considered a hazardous substance and appropriate safety measures should be taken.
-When handling, follow good laboratory practices and wear appropriate personal protective equipment, such as laboratory gloves and eye protection equipment.
-Avoid inhaling the dust or gas of the compound, avoid skin contact and intake.
-In case of accidental contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-The compound should be stored in a dry, well-ventilated place, away from fire and oxidizing agents.
Nature:
-Appearance: The compound was a white crystalline solid.
-Solubility: Insoluble in water, but soluble in organic solvents such as ethanol and dimethylformamide.
-Melting point: about 69-72 ℃.
-Stability: relatively stable under normal storage conditions.
Use:
-Drug: 1-[(2-chlorophenyl) methyl]-2-piperazine methanol, as a drug intermediate, can be used to synthesize drugs, with antidepressant and anti-anxiety properties.
Method:
The synthesis of 1-[(2-chlorophenyl) methyl]-2-piperazinemethanol is usually carried out by the following steps:
1.2-Chloroanisole reacts with piperazine to form 1-[(2-chlorophenyl) methyl]-2-piperazine methyl ether.
2.1-[(2-chlorophenyl) methyl]-2-piperazine methyl ether is reduced to 1-[(2-chlorophenyl) methyl]-2-piperazine methanol.
Safety Information:
- 1-[(2-Chlorophenyl) methyl]-2-piperazinemethanol should be considered a hazardous substance and appropriate safety measures should be taken.
-When handling, follow good laboratory practices and wear appropriate personal protective equipment, such as laboratory gloves and eye protection equipment.
-Avoid inhaling the dust or gas of the compound, avoid skin contact and intake.
-In case of accidental contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-The compound should be stored in a dry, well-ventilated place, away from fire and oxidizing agents.
Last Update：2024-04-09 15:17:51
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